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The virus, called adeno-associated virus type 2, or AAV-2, infects an estimated 80 percent of the population.

AAV-2 is a small virus that cannot replicate itself without the help of another virus, but with the help of a second virus it kills cells. In this case it effectively kills cancerous cells, and apparently, with no harmful side-effects on normal cells.” Lab results suggest that adeno-associated virus type 2, which infects the majority of the population but has no known ill effects, kills multiple types of cancer cells, yet it has no effect on healthy cells,” said Craig Meyers, a professor of microbiology and immunology at the Penn State College of Medicine in Pennsylvania.”

It is believed that AAV-2 recognizes that the cancer cells are abnormal and destroys them. This suggests that AAV-2 has great potential to be developed as an anti-cancer agent.

For their study, Meyers and colleagues first infected a batch of human cells with HPV, some strains of which cause cervical cancer. They then infected these cells and normal cells with AAV-2. After six days, all the HPV-infected cells died. The same thing happened with cervical, breast, prostate and squamous cell tumor cells. All are cancers of the epithelial cells, which include skin cells and other cells that line the insides and outsides of organs.”

One of the most compelling findings is that AAV-2 appears to have no pathologic effects on healthy cells,” Meyers said.” So many cancer therapies are as poisonous to healthy cells as they are to cancer cells.A therapy that is able to distinguish between healthy and cancer cells could be less difficult to endure for those with cancer.” AAV-2 is being studied intensively as a gene therapy vector — a virus modified to carry disease-correcting genes into the body. Gene therapy researchers favor it because it does not seem to cause disease or immune system reaction on its own.